More From Our Collaborators

Michael

Steroids and Exercise in DMD

Impact and Interplay of Corticosteroid Regimen and Exercise Training on DMD Muscle Function

About: The purpose of this study is to investigate the therapeutic potential of low‐dose weekend steroid use alone or in combination with exercise training in boys with DMD. Current standard of care for patients with DMD involves steroids, which when taken daily, lead to numerous side effects. Recent evidence suggests that weekend‐only use of steroids may have equal benefit without the negative side effects. In addition, appropriate exercise may magnify the beneficial effects of steroids.

Ages Eligible for Study: 5-8 years (Child only)

Sexes Eligible for Study: Male

Status:  Actively recruiting. 

For more information, please click on this link to open the study specific advertisement. 


Blood Biomarker and Exercise in DMD

Use of a biomarker approach to optimize rehabilitation strategies for DMD patients

About: 

Current research is aimed at discovering markers in the blood that reflect the amount of DMD damage in the muscle. It is important to have these ‘blood biomarkers’ so that doctors and scientists can measure how muscle in patients with DMD responds to things like physical activity and exercise, or therapeutic strategies that may be developed in the near future. The purpose of this research study is to measure muscle proteins that are in the blood before and after a controlled bout of physical activity. You are being asked to be in this research study because you have

The purpose of this study is to measure markers in the blood that reflect the amount of damage in DMD muscle, before and after a controlled bout of physical activity. Investigation of these ‘blood biomarkers’ is important so that doctors and scientists can understand how muscle in patients with DMD responds to things like physical activity and exercise, or therapeutic strategies that are being developed.

Ages Eligible for Study: 8 years and older (Ambulant and Non-ambulant)

Sexes Eligible for Study: Male

Status:  Actively recruiting. 

For more information, please click on this link to open the study specific advertisement. 


ImagingDMD

ImagingDMD

The study, known as “ImagingDMD” is a joint effort between researchers at the University of Florida, The Children’s Hospital of Philadelphia, Oregon Health and Science University, and Shriners Hospital for Children-Portland to investigate the potential of magnetic resonance imaging (MRI) to non-invasively monitor disease progression in Duchenne muscular dystrophy. Families interested in learning more about the study are encouraged to contact the ImagingDMD Team.